We've also seen a lot of research that talks about the effects of joblessness on deaths of despair which includes overdoses, suicides and alcohol misuse. In short, places that experienced high level of joblessness are also places that experience high levels of deaths of despair. http://www.solvecast.com/articles/detail/15292-opioid-epidemic-tackling-community-decay-and-loneliness-with-sarmed-rashid